The fall of Syrian dictator Bashar al-Assad, the culmination of years of civil war, has given way to a power vacuum with different factions protecting their own interests – and vying for power in the Middle Eastern nation. 

The U.S., worried about the resurgence of an ISIS stronghold, has struck targets associated with the Islamic State in central Syria. 

Turkey, which controls a zone of Syria on its northern border, has continued to attack U.S.-backed Kurdish forces. 

Both work with different proxy groups. 

Here’s a look at the different forces vying for control in the region:

Hayat Tahrir al-Sham (HTS)

HTS was the key faction behind the fall of Damascus and the fleeing of Assad, and now controls the capital city. But the Islamist militant group is far from a U.S. ally – its leader, Abu Mohammed al-Golani, has a $10 million U.S. bounty on his head and has been designated a terrorist since 2013. The group governed just a sliver of northwest Syria in Idlib. 

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The group, founded as an al Qaeda affiliate, still remains largely aligned with al Qaeda but focuses on establishing fundamentalist Islamic rule in Syria rather than a global caliphate. 

The U.N., U.S. and Turkey all designate HTS as a terrorist organization. The group, in recent years, has worked to soften its image and lobbied to be delisted as a terrorist group, highlighting its government services in Idlib and promising to protect religious and cultural sites, even churches, in Aleppo. 

Experts believe Turkey, which has long looked to topple Assad, may have been at play in HTS’ offensive. 

Syrian government forces 

Syria’s forces loyal to Assad have staved off coup attempts since 2011, often through violent crackdowns on protests and rebellion. 

By 2020, government troops backed by Iran, Russia and Lebanese Hezbollah had pushed rebel forces back to the northwest corner of Syria. 

In the waning days of November, rebel factions swiftly overpowered government troops, seizing control of Aleppo – a city previously reclaimed by Assad’s forces in 2016. Eight days later, the insurgents successfully captured not only Aleppo, but also Hama, Homs and Damascus.

On Monday, HTS granted Assad’s forces “a general amnesty for all military personnel conscripted under compulsory service.”

“Their lives are safe and no one may assault them,” the group said in a statement.

Syrian National Army (SNA) 

The SNA is a loosely bound coalition of Turkish-backed forces primarily intent on fighting Kurdish forces. But the coalition, which carries out Turkish President Recep Erdogan’s anti-Assad efforts, was also involved in the fall of Damascus. The groups have – in the past – also battled HTS and other Islamic State terrorists. 

The SNA coalition believes U.S.-backed Kurdish forces in Syria to be linked to Turkey’s Kurdistan Workers’ Party (PKK), a militant group that has launched Kurdish nationalist attacks in Turkey.

Syrian Democratic Forces (SDF) 

SDF is a coalition of U.S.-backed Kurdish forces, centered in northeastern Syria. They have long worked alongside the U.S. in battling Islamic State forces in Syria.

In addition to fighting the Islamic State, they’ve been fending off attacks from Turkish-backed fighters. 

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Kurdish forces were not involved in the offensive that toppled Assad, but they hailed the offensive campaign. 

“In Syria, we are living through historic moments as we witness the fall of the authoritarian regime in Damascus. This change presents an opportunity to build a new Syria based on democracy and justice that guarantees the rights of all Syrians,” said Mazlum Abdi, the commander of the SDF, on Sunday morning. 

Turkey 

After relatively friendly relations with Syria throughout the early 2000s, Turkey condemned Assad over the violent 2011 crackdown on protesters. 

While Turkey and the U.S. are allies – bound to protect each other through NATO – they are on opposing sides in Syria, even as both celebrated Assad’s downfall. The Turkish military fired on U.S.-backed forces in Syria over the weekend, where fighting erupted between rebel groups in Manbij, a Kurdish-controlled city near Syria’s border with Turkey. Turkey has long had a goal of pushing the Kurds away from its border, and is looking to use the current turmoil to capture control along the border and decimate the Kurdish population there.  

Kurdish separatists have fought Turkey for years, looking to carve out their own autonomous nation. 

Russia

Russia has long propped up the Assad regime, and days ago granted the ousted leader asylum.

Since 2015, Russia has effectively acted as Assad’s air force, but its capacity to intervene on the dictator’s behalf has diminished since resources were needed for the war with Ukraine. 

Iran 

Iran was Assad’s biggest supporter, providing arms and military advice and directing its proxy Lebanese Hezbollah to fight the insurgents. But Hezbollah had to direct its troops back to Lebanon to fight Israel, leaving Assad’s forces in a weakened position. 

HTS leader al-Golani lamented in a speech on Sunday that Syria had become “a playground for Iranian ambitions.”

Israel

Israeli Prime Minister Benjamin Netanyahu credited his forces’ weakening of Hezbollah for playing a key role in the fall of Assad. Israel has consistently launched strikes against Syria with the strategic aim of disrupting the channels Iran uses to supply arms to Hezbollah.

After Assad’s fall, Israel, on Sunday, struck Assad’s chemical weapons facilities within Syria, for fear of what hands they may fall into in his absence. 

Israel also captured control of a buffer zone within the Golan Heights, the first time they’ve captured territory in Syria since the war in 1973. 

The Israel Defense Forces (IDF) moved in on Sunday and told residents to remain in their homes until further notice. They said they needed to capture the territory to ensure border security. 

They also captured Mount Hermon – the highest point on the border between the two countries and a blind spot in their defenses that Iran had been exploiting to send low-flying drones. 

U.S. 

Some 900 U.S. troops remain in Syria, where they are partnered with the SDF to fight ISIS. 

On Sunday, President Biden said U.S. troops would remain there to “ensure stability.” 

The U.S. carried out dozens of precision strikes on more than 75 ISIS targets in central Syria over the weekend to prevent the terrorist group from exploiting the unrest to rebuild. 

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“We’re clear-eyed about the fact that ISIS will try to take advantage of any vacuum to re-establish its capability to create a safe haven,” Biden said. “We will not let that happen.”

Biden said the U.S. would support Syria’s neighbors – Jordan, Lebanon, Iraq and Israel – “should any threat arise from Syria during this transition.”

The president added that the fall of Assad created a “historic opportunity for the long-suffering people of Syria.”